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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLDN3
All Species:
15.15
Human Site:
S209
Identified Species:
37.04
UniProt:
O15551
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15551
NP_001297.1
220
23319
S209
R
S
T
G
P
G
A
S
L
G
T
G
Y
D
R
Chimpanzee
Pan troglodytes
XP_001147969
220
23254
S209
R
S
T
G
P
G
A
S
L
G
T
G
Y
D
R
Rhesus Macaque
Macaca mulatta
XP_001112442
220
23463
S209
R
S
T
G
P
G
A
S
M
G
T
A
Y
D
R
Dog
Lupus familis
XP_546920
210
22073
A195
R
A
D
K
P
Y
S
A
K
Y
S
A
A
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0G9
219
23266
G208
R
S
T
G
P
G
T
G
T
G
T
A
Y
D
R
Rat
Rattus norvegicus
Q63400
219
23296
G208
R
S
T
G
P
G
T
G
T
G
T
A
Y
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509958
214
22761
S203
V
M
Y
S
A
A
R
S
S
G
P
S
Y
D
R
Chicken
Gallus gallus
NP_989533
214
23072
S203
V
A
Y
S
A
P
R
S
A
V
T
S
Y
D
K
Frog
Xenopus laevis
NP_001087400
213
22866
T203
A
Y
T
A
A
R
S
T
N
P
G
Y
D
K
K
Zebra Danio
Brachydanio rerio
Q9YH91
208
22187
S194
K
N
E
G
R
A
Y
S
V
K
Y
S
A
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.1
95.9
71.8
N.A.
90.9
90.4
N.A.
80.4
74
70.4
60
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
93.1
97.2
83.6
N.A.
95.4
95
N.A.
90.9
89
89.5
76.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
20
N.A.
73.3
73.3
N.A.
33.3
26.6
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
46.6
N.A.
73.3
73.3
N.A.
33.3
40
26.6
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
0
10
30
20
30
10
10
0
0
40
20
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
0
10
70
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
60
0
50
0
20
0
60
10
20
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
10
0
0
0
0
10
10
0
0
0
10
20
% K
% Leu:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
60
10
0
0
0
10
10
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
60
0
0
0
10
10
20
0
0
0
0
0
0
0
80
% R
% Ser:
0
50
0
20
0
0
20
60
10
0
10
30
0
0
0
% S
% Thr:
0
0
60
0
0
0
20
10
20
0
60
0
0
0
0
% T
% Val:
20
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
20
0
0
10
10
0
0
10
10
10
70
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _